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Current Trends in Science and Technology

an Open Access Publication ISSN: 0976-9730 | 0976-9498

Medical

To TO STUDY THE CHANGES IN OPTIC CUP DISC RATIO IN PRIMARY OPEN ANGLE GLAUCOMA BEFORE AND AFTER TRABECULATOMY

Yash Pal Sharma
Civil Hospital Rohru, Distt Shimla, H.P. 171214 India
Dr. Vinod Sharma
Civil Hospital Rohru, Distt Shimla, H.P. 171214 India
Dr. M. L. Pandey
Civil Hospital Rohru, Distt Shimla, H.P. 171214 India
Dr. Kalpana Sharma
Civil Hospital Rohru, Distt Shimla, H.P. 171214 India
Online First: February 25, 2020
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Abstract

Purpose:  To study the relation between measurements of optic cup disc ratio at 1week, 1 and 3 month post-operatively in a population of clinical patients with primary open angle glaucoma undergone trabeculectomy in the Sub-Himalayan region.


Methods: Patient sample size consisting of n=27 were accessed for primary open angle glaucoma. The sample population consists of adults with open anterior chamber angle and with demonstrative RNFL damage, with corresponding visual field loss. Average optic cup disc ratio measurements were taken on Topcon 3D OCT-1 Maestro within a week before surgery and at 1 week, 1 and 3 month post operatively. Pre and post operative value were analyzed using Repeated Measure ANOVA with Bonferroni correction.


Results: It was observed that in the patients during the pre-operative period optic cup disc ratio came out to be 0.7896 ±0.7004. In the first week post operatively it was observed that the optic cup disc ratio came to be equal to 0.7563 ± 0.13342 (p=0.021). During the first month observational period it came equal to 0.73 ±0.1321 (p=0.020). In third month the optic cup disc ratio came to be   0.7004 ±0.18039 (p=0.000).


Conclusions: Significant changes were observed in optic cup disc ratio, post-operatively following Trabeculectomy. Optic cup disc ratio showed improvement in 1 week 1and 3 month post operatively.

Keyword : Optical Coherence Tomography; Trabeculectomy; Optic Cup Disc Ratio, Primary Open Angle Glaucoma;

  Submitted
Feb 7, 2020
Published
Feb 25, 2020
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References

1. A.K Khurrana, Indu Khurrana. Anatomy and Physiology of Eye, 2nd Edition. 2014. 2. Brad Bowling. Kanski‘s Clinical Ophthalmology: A Systematic Approach, 8th Edition. 3. Young H. Kwon, John H. Fingert, Markus H. Kuehn, Wallace L.M. Alward. Primary Open-Angle Glaucoma. N Engl J Med. 2009 March 12; 360(11): 1113–1124. 4. Shum JW, Leung DY. Surgical Decisions in Primary Open Angle Glaucoma with Low or Normal Tension. Journal of Current Glaucoma Practice, September-December 2013; 7(3):121-127. 5. Monica Gandhi, Suneeta Dubey. Evaluation of the Optic Nerve Head in Glaucoma. Journal of Current Glaucoma Practice, September-December 2013; 7(3):106-114 107. 6. N Raghu, SS Pandav, S Kaushik, P Ichhpujani and A Gupta. Effect of Trabeculectomy on RNFL thickness and optic disc parameters using optical coherence tomography. Eye (2012) 26, 1131–1137 7. Teresa C. Chen. Spectral domain optical coherence tomography in glaucoma: qualitative and quantitative analysis of the optic nerve head and retinal nerve fiber layer (an AOS thesis). Trans Am Ophthalmol Soc. 2009; 107:254-281 8. NHMRC Guidelines for the Screening, Prognosis, Diagnosis, Management and Prevention of Glaucoma 2010: 39-45, 65-88. 9. M Figus, S Lazzeri, M Nardi, MP Bartolomei, A Ferreras and P Fogagnolo Short-term changes in the optic nerve head and visual field after trabeculectomy, Eye (2011) 25, 1057–1063. 10. A. Paranhos Jr., M.C. Lima, S. Salim, J. Caprioli and M.B. Shields. Trabeculectomy and optic nerve head topography, Brazilian Journal of Medical and Biological Research, 2006; 39; 149-155. 11. Inci Irak, Linda Zangwill, Valerie Garden, Sima Shakiba and Robert N. Weinreb. Change in Optic Disk Topography after Trabeculectomy, American Journal of Ophthalmology 1996 (Nov); 122:690-695. 12. R. Rand Allingham, Shields Textbook of Glaucoma, Sixth Edition. 2012.
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References

1. A.K Khurrana, Indu Khurrana. Anatomy and Physiology of Eye, 2nd Edition. 2014.
2. Brad Bowling. Kanski‘s Clinical Ophthalmology: A Systematic Approach, 8th Edition.
3. Young H. Kwon, John H. Fingert, Markus H. Kuehn, Wallace L.M. Alward. Primary Open-Angle Glaucoma. N Engl J Med. 2009 March 12; 360(11): 1113–1124.
4. Shum JW, Leung DY. Surgical Decisions in Primary Open Angle Glaucoma with Low or Normal Tension. Journal of Current Glaucoma Practice, September-December 2013; 7(3):121-127.
5. Monica Gandhi, Suneeta Dubey. Evaluation of the Optic Nerve Head in Glaucoma. Journal of Current Glaucoma Practice, September-December 2013; 7(3):106-114 107.
6. N Raghu, SS Pandav, S Kaushik, P Ichhpujani and A Gupta. Effect of Trabeculectomy on RNFL thickness and optic disc parameters using optical coherence tomography. Eye (2012) 26, 1131–1137
7. Teresa C. Chen. Spectral domain optical coherence tomography in glaucoma: qualitative and quantitative analysis of the optic nerve head and retinal nerve fiber layer (an AOS thesis). Trans Am Ophthalmol Soc. 2009; 107:254-281
8. NHMRC Guidelines for the Screening, Prognosis, Diagnosis, Management and Prevention of Glaucoma 2010: 39-45, 65-88.
9. M Figus, S Lazzeri, M Nardi, MP Bartolomei, A Ferreras and P Fogagnolo Short-term changes in the optic nerve head and visual field after trabeculectomy, Eye (2011) 25, 1057–1063.
10. A. Paranhos Jr., M.C. Lima, S. Salim, J. Caprioli and M.B. Shields. Trabeculectomy and optic nerve head topography, Brazilian Journal of Medical and Biological Research, 2006; 39; 149-155.
11. Inci Irak, Linda Zangwill, Valerie Garden, Sima Shakiba and Robert N. Weinreb. Change in Optic Disk Topography after Trabeculectomy, American Journal of Ophthalmology 1996 (Nov); 122:690-695.
12. R. Rand Allingham, Shields Textbook of Glaucoma, Sixth Edition. 2012.
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