With Russian annexation of Crimea, the European Union (EU), United States of America (USA) and many other western countries impose Sanctions on Russia. For that reason the Russia has to Strength its Eastern policy. In East the best option for Russia is Central Asia. The Russia has invested significant resources in retaining influence over the region. The strategy which Moscow is applying is that it has emerging slowly and reluctantly with its new role in the Region.Russia seemed likely to remain for now the most prominent external power in Central Asia in terms of its high-level political relationships and its security cooperation in the Region.In this context the present study explore the possibilities of greater ties between Central Asia and Russia. The paper further examines the Russiaâ€™s interest in Central Asia that will be largely focused on trade, natural resources and other purposes.