Nucleic Acid Based Therapeutic Delivery System

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Sakshi Minocha Manoj Sharma Ashish Agarwal Anil Kumar Gupta
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Abstract

Nucleic acids have change biomedical research and become essential research tools. Nucleic acid molecules are useful in a variety of biochemical, diagnostic, and therapeutic applications. Gene therapy is a technique used to correct defective genes which are responsible for disease development. Gene therapy involves the transference of new genetic material to the cell for obtaining a therapeutic benefit, which offers new option for the treatment of various diseases. Nucleic acid-based molecules (deoxyribonucleic acid, complementary deoxyribonucleic acid, complete genes, ribonucleic acid, and oligonucleotides) are used as research tools within the gene therapy and in molecular medicine

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MINOCHA, Sakshi et al. Nucleic Acid Based Therapeutic Delivery System. International Journal of Current Trends in Science and Technology, [S.l.], v. 8, n. 03, p. 20181-20195, mar. 2018. ISSN 0976-9730. Available at: <http://currentsciences.info/index.php/ctst/article/view/366>. Date accessed: 20 june 2018. doi: https://doi.org/10.15520/ctst.v8i03.366.pdf.
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Pharmaceutical Sciences

References

1. R. Sharma and V. M. Katoch. Designing of oligonucleotides: probes and primers for diagnosis, epidemiology and research in medicine.J. Commun. Dis.38:305–316 (2006).
2. M. Jayapal and A. J. Melendez. DNA microarray technology for target identification and validation. Clin. Exp. Pharmacol. Physiol.33:496–503 (2006).
3. Haussecker D.Kay M.A. RNA interference. Drugging RNAi Science 2015 3471069 1070.
4. SuhrO.B.Coelho T.BuadesJ. Pouget J. ConceicaoI. BerkJ. SchmidtH. Waddington-CruzM. Campistol J. M.Betten court B.R.et al. Efficacy and safety of patisiran for familial amyloidotic polyneuropathy: a phase II multi-dose studyOrphanet J. Rare Dis.201510109.
5. https://www.sciencedirect.com/topics/biochemistry-genetics-and molecular-biology/gene-therapy.
6. Walther W, Stein U. Viral vectors for gene transfer: a review of their use in the treatment of human diseases. Drugs. 2000; 60:249271. doi: 10.2165/00003495-200060020-00002.
7. Medina-Kauwe LK, Xie J, Hamm-Alvarez S. Intracellular trafficking of nonviral vectors. Gene Ther. 2005; 12:1734–1751. doi: 10.1038/sj.gt.3302592.
8. Neumann E, Schaefer-Ridder M, Wang Y, Hofschneider PH. Gene transfer into mouse lyoma cells by electroporation in high electric fields. Embo J. 1982;1:841–845.
9. Titomirov AV, Sukharev S, Kistanova E. In vivo electroporation and stable transformation of skin cells of newborn mice by plasmid DNA. Biochim Biophys Acta. 1991; 1088:131–134.
10. Mair L, Ford K, Alam MR, Kole R, Fisher M, Superfine R, et al. Size-Uniform 200 nm Particles: Fabrication and Application to Magnetofection. J Biomed Nanotechnol. 2009; 5:182–91.
11. Liu D, Ren T, Gao X. Cationic transfection lipids. Curr Med Chem. 2003;10:1735–7.
12. Khalil IA, Kogure K, Akita H, Harashima H. Uptake pathways and subsequent intracellular trafficking in nonviral gene delivery. Pharmacol Rev. 2006;58:32–45.
13. Yang J, Chen S, Huang L, Michalopoulos GK, Liu Y. Sustained expression of naked plasmid DNA encoding hepatocyte growth factor in mice promotes liver and overall body growth. Hepatology. 2001;33:848–59.
14. Kim HJ, Greeenleaf JF, Kinnick RR, Bronk JT, Bolander ME. Ultrasound-mediated transfection of mammalian cells. Hum Gene Ther. 1996;7:1339–46.
15. https://pubs.acs.org/doi/abs/10.1021/jm500330k
16. Miller DG, Adam MA, Miller AD. Gene transfer by retrovirus vector occurs only in cells that are actively replicating at the time of infection. Mol Cell Biol 1990; 10: 4139-42
17. Gilboa E, Eglitis MA, Kantoff PW, et al. Transfer and expression of cloned genes using retroviral vectors. Biotechniques 1986; 4: 504-12
18. Guild BC, Finer MF, Housman DE, et al. Develoment of retroviral vectors useful for expressing genes in cultured embryonal cells and hematopoietic cells in vivo. J Virol 1988; 62: 3795-801 Guild BC, Finer MF, Housman DE, et al. Develoment of retroviral vectors useful for expressing genes in cultured embryonal cells and hematopoietic cells in vivo. J Virol 1988; 62:3795-801
19. J.D. Watson, F.H.C. Crick, The structure of DNA, Cold Spring Harb. Symp. Quant. Biol. 18 (1953) 123–131.
20. L.M. Smith, Nanostructures — the manifold faces of DNA, Nature 440 (2006) 283–284.
21. C. Zhang, M. Su, Y. He, X. Zhao, P.A. Fang, A.E. Ribbe, W. Jiang, C.D. Mao, Conformational flexibility facilitates self-assembly of complex DNA nanostructures, Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 10665–10669.
22. D.E. Ingber, Tensegrity: the architectural basis of cellular mechanotransduction, Annu. Rev. Physiol. 59 (1997) 575–599.
23. Mathews QL, Curiel DT.Grne Therapy: Human Gemline Genetics Modifications-Assessing the Scientific, Socioethical, and Religious Issues. Southern Medical Journal 2007; 100:98-100
24. Bank A. Human Somatic Cell Gene Therapy 1996; 18:999-1007.
25. Wang C-Y, Li F, Yang Y, Guo H-Y, Wu C-X, Wang S (2006) Recombinant baculovirus containing the Diphtheria toxin A gene for malignant glioma therapy. Cancer Res 66:5798–5806
26. Gao WT, Soloff AC, Lu XH, Montecalvo A, Nguyen DC, Matsuoka Y et al (2006) Protection of mice and poultry from lethal H5N1 avian influenza virus through adenovirus-based immunization. J Virol 80: 1959–1964
27. Evans CH, Ghivizzani SC, Herndon JH, Wasko MC, Reinecke J, Wehling P et al (2000) Clinical trials in the gene therapy of arthritis. Clin Orthop 379:S300–S307
28. J.H. Chan, S. Lim , W.S. Wong. Antisense oligonucleotides: from design to therapeutic application. Clin Exp Pharmacol Physiol, 33[5-6], 2000, 533-40.
29. K.J.Scanlon, Y.Ohta, H. Ishida, H. Kijima , T.Ohkawa , A. Kaminski, et al. Oligonucleotide-mediated modulation of mammalian gene expression. FASEB J., 9[13], 1995, 1288-96.
30. P. Sazani, R. Kole. Therapeutic potential of antisense oligonucleotides as modulators of alternative splicing. J Clin Invest.,112[4], 2003, 481-6.
31. Dr.Bharti Bhandari, Dr.Deepti Chopra Department of Physiology, AIIMS, Jodhpur, Department of Pharmacology, HIMSR, Jamia Hamdard Antisense Oligonucleotide: Basic Concept and its Therapeutic ApplicationQuest JournalsJournal of Research in Pharmaceutical ScienceVolume 2 ~ Issue 3 (2014) pp: 01-13ISSN(Online) : 2347-2995
32. Engelhard, H.H., Antisense oligodeoxynucleotide technology: potential use for the treatment of malignant brain tumors. Cancer control. 1998, (5), 163–170.
33. Hammond, S.M., Bernstein, E., Beach, D., An RNA directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature. 2000, (404), 293–296.
34. Erdal Cevher, Ali Demir Sezer and Emre Şefik ÇağlarGene Delivery Systems: Recent Progress in Viral and Non-Viral Therapy
35. Al-Dosari MS, Gao X. (2009). Nonviral Gene Delivery: Principles, Limitations, and Recent Progress. American Association of Pharmaceutical Scientist Journal; 11; 671-681.
36. Altaner C (2008). Prodrug cancer gene therapy. Cancer Letters; 270; 191–201.
37. Armendáriz-Borunda J, Bastidas-Ramírez BE, Sandoval-Rodríguez A, González-Cuevas J, Gómez-Meda B, García-Bañuelos J. (2011).
38. Production of first generation adenoviral vectors for preclinical protocols: Amplification, purification and functional titration. Journal of Bioscience and Bioengineering; 112415–421.